Coral bleaching has impacted reefs worldwide and the predictions of near‐annual bleaching from over two decades ago have now been realized. While technology currently provides the means to predict large‐scale bleaching, predicting reef‐scale and within‐reef patterns in real‐time for all reef users is limited. In 2020, heat stress across the Great Barrier Reef underpinned the region's third bleaching event in 5 years. Here we review the heterogeneous emergence of bleaching across Heron Island reef habitats and discuss the oceanographic drivers that (...) underpinned variable bleaching emergence. We do so as a case study to highlight how reef end‐user groups who engage with coral reefs in different ways require targeted guidance for how, and when, to alter their use of coral reefs in response to bleaching events. Our case study of coral bleaching emergence demonstrates how within‐reef scale nowcasting of coral bleaching could aid the development of accessible and equitable bleaching response strategies on coral reefs. Also see the video abstract here: https://youtu.be/N9Tgb8N-vN0. (shrink)

Clinical trials for acute conditions such as myocardial infarction and stroke pose challenges related to informed consent due to time limitations, stress, and severe illness. Consent processes shou...

Graphical AbstractDriving patterns of coral bleaching over reefs are a suite of biophysical interactions where the physical environment modulates organism response through an interplay with intrinsic biological functioning. Flow conditions over reefs can mitigate the physiological impacts of thermal stress across multiple spatial scales. More details can be found in article number 1800226 by Charlotte E. Page et al., Seeking Resistance in Coral Reef Ecosystems: The Interplay of Biophysical Factors and Bleaching Resistance under a Changing Climate, DOI: 10.1002/bies.201800226.

If we are to ensure the persistence of species in an increasingly warm world, of interest is the identification of drivers that affect the ability of an organism to resist thermal stress. Underpinning any organism's capacity for resistance is a complex interplay between biological and physical factors occurring over multiple scales. Tropical coral reefs are a unique system, in that their function is dependent upon the maintenance of a coral–algal symbiosis that is directly disrupted by increases in water temperature. A (...) number of physical factors have been identified as affecting the biological responses of the coral organism under broadscale thermal anomalies. One such factor is water flow, which is capable of modulating both organismal metabolic functioning and thermal environments. Understanding the physiological and hydrodynamic drivers of organism response to thermal stress improves predictive capabilities and informs targeted management responses, thereby increasing the resilience of reefs into the future. (shrink)

To our knowledge, this is one of the first studies to test different theoretical models of working memory in childhood based on a computerized assessment. We tested this across several countries: Argentina, Brazil, Canada, Italy, and UK. The present study addressed the wider macro-cultural context and how this impacts working memory. We used two economic indices to characterize the participating countries and ranked the countries based on the Global Index of Cognitive Skills and Educational Attainment. Children between 5 and 10 (...) years completed the same set of short-term and working memory tests. There were two main findings. First, there was a similar pattern in verbal working memory across countries, which suggests that this skill may be relatively consistent across different cultural groups. In contrast, the pattern for visuo-spatial working memory was different across countries, which may explained by cultural differences and educational rankings of the countries. The second main finding was that both a domain-general model and a domain-specific model provided a reasonably good fit with the data, there was the high relationship between the verbal and visuo-spatial working memory constructs across the countries in the latter model. Thus, it may be a more parsimonious choice to rely on a three-factor model. The data also suggest culture-similar patterns in a computerized assessment of working memory. (shrink)

The neural representation of a repeated stimulus is the standard against which a deviant stimulus is measured in the brain, giving rise to the well-known mismatch response. It has been suggested that individuals with dyslexia have poor implicit memory for recently repeated stimuli, such as the train of standards in an oddball paradigm. Here, we examined how the neural representation of a standard emerges over repetitions, asking whether there is less sensitivity to repetition and/or less accrual of “standardness” over successive (...) repetitions in dyslexia. We recorded magnetoencephalography as adults with and without dyslexia were passively exposed to speech syllables in a roving-oddball design. We performed time-resolved multivariate decoding of the MEG sensor data to identify the neural signature of standard vs. deviant trials, independent of stimulus differences. This “multivariate mismatch” was equally robust and had a similar time course in the two groups. In both groups, standards generated by as few as two repetitions were distinct from deviants, indicating normal sensitivity to repetition in dyslexia. However, only in the control group did standards become increasingly different from deviants with repetition. These results suggest that many of the mechanisms that give rise to neural adaptation as well as mismatch responses are intact in dyslexia, with the possible exception of a putatively predictive mechanism that successively integrates recent sensory information into feedforward processing. (shrink)

Few historical figures have been more important in modeling the ideal of impartial critical scholarship than Erasmus of Rotterdam (1469-1536). Yet his critical scholarship, though beholden to no one, was not dispassionate. James Tracy shows how Erasmus the scholar sought through his writings to promote the moral and religious renewal of Christian society. Tracy finds the genesis of the humanist's notion of a "Christian republic" of pious and learned individuals in his "Burgundian," or Low Countries, roots. Erasmus's vision of reform, (...) Tracy argues, sprung from a humanist tradition focusing on the importance of teaching (_doctrina_), a tradition from which Erasmus departed in his optimism about human nature and his deep suspicion of the powers that be. Amid the storms of Reformation controversy, he pruned back the "dissimulation" by which he had thought to convey different meanings to different readers, yet in the end he could not control the way his words were read. If Erasmus's scholarly ideal carries an enduring fascination, so too does his dilemma as a man of circumspection who would also be a reformer. (shrink)

People with a repressive coping style are highly motivated to defend themselves against self-concept threats. But what kinds of unfavourable personal characteristics are they most focused on avoiding? Weinberger (Citation1990) suggested that repressors are primarily concerned with seeing themselves (and having others see them) as calm, unemotional people who are not prone to experiencing negative affect. A content analysis of the actual (self-ascribed) and undesired attributes of 349 male and female college students, however, provided no support for that hypothesis. Instead, (...) relative to other participants, repressors’ undesired selves consisted more of traits exemplifying disagreeableness (as defined by the five-factor model). Repressors might not engage in affective self-regulation for its own sake, but because it allows them to control expression of traits with which they are more directly concerned. (shrink)

While tens of thousands of people across the United States serve on hospital and other healthcare ethics committees , almost no carefully prepared educational material exists for HEC members. Ethics by Committee is a one volume collection of chapters developed exclusively for this educational purpose. Experts in bioethics, clinical consultation, health law, and social psychology from across the country contribute chapters on ethics consultation, education, and policy development.

We suggest edits to Part Four of the Ethical and Religious Directives (ERDs) to help the US bishops address and clarify essential Church teachings on specific beginning-of-life issues facing Catholic health care today. As a teaching tool, Part Four must be updated so that Catholic health care professionals and the lay faithful can understand and apply Church teachings to new ethical challenges. Further, more direction and clarity from the ERDs is needed in applying general principles to assisted procreative technologies, pre- (...) and post-viability induction of labor, ectopic pregnancies, genetic screening and diagnosis, and contraception. Catholic health care clinicians and administrators also need to receive ongoing instruction on the ERDs’ teachings as well as the theological and philosophical rationales that undergird them. (shrink)

Tacitus traces a series of conflicts between Agrippina the Elder and her father-in-law Tiberius. After the death of her husband Germanicus in Syria, Agrippina returned to Rome with their children. Germanicus' lingering popularity with the armies and people meant that his widow Agrippina and their children enjoyed a level of popular support as well—one that eventually became a threat in Tiberius' mind. Agrippina, moreover, refused to embrace the modest, retiring role that her father-in-law expected of her. Tiberius was, moreover, ‘never (...) gentle toward the house of Germanicus’ and his concerns were augmented by the machinations of Sejanus, who reported that the people were dividing themselves into factions, some even calling themselves members of the partes Agrippinae. The combination of Agrippina's high birth—the only still-living grandchild of Augustus—and her status as widowed daughter-in-law of the emperor, therefore mother of the emperor's probable heir, along with her persistent independence and sometimes unfeminine strength of character made her seem an intolerable political threat. This paper examines the culmination of these conflicts, when Agrippina is subjected to criminal prosecution and penalty in a.d. 27 and 29 at the instigation of Sejanus, with the overt approval of Tiberius. Of primary concern is the timing and the order of the charges brought against Agrippina. (shrink)

Ample research demonstrates that parents’ experience-based mental representations of attachment—cognitive models of close relationships—relate to their children’s social-emotional development. However, no research to date has examined how parents’ attachment representations relate to another crucial domain of children’s development: brain development. The present study is the first to integrate the separate literatures on attachment and developmental social cognitive neuroscience to examine the link between mothers’ attachment representations and 3- to 8-year-old children’s brain structure. We hypothesized that mothers’ attachment representations would relate (...) to individual differences in children’s brain structures involved in stress regulation—specifically, amygdala and hippocampal volumes—in part via mothers’ responses to children’s distress. We assessed 52 mothers’ attachment representations and children’s brain structure. Mothers’ secure base script knowledge was significantly related to children’s smaller left amygdala volume but was unrelated to hippocampal volume; we found no indirect links via maternal responses to children’s distress. Exploratory analyses showed associations between mothers’ attachment representations and white matter and thalamus volumes. Together, these preliminary results suggest that mothers’ attachment representations may be linked to the development of children’s neural circuitry related to stress regulation. (shrink)

1.Idéologie proprement dite. Introd. et appendices par H. Gouhier.--2. Grammaire.

The predominance of patriarchally-based structures in Kristeva's work sets up an uncomfortable dichotomy for feminist critics. Her 1979 essay `Le temps des femmes' (translated as `Women's Time' in 1981) most explicitly articulates her own approach to feminism, addressing women's troubled relationship to patriarchy in terms of time and space. Kristeva identifies three distinct positions in feminist thought: `equality', `difference' and an anticipated `third generation' feminism that integrates the previous two attitudes, representing what she defines as a new `signifying space'. The (...) value of the `third space' is that it offers a method for proceeding beyond the either/or status offered by previous stages of feminist thought and analysis, challenging gender identity per se and bringing out the singularity of each individual subject. I explore ways of reading from the third space through examples of the `Cassandra' myth and H.D.'s epic poem Helen in Egypt (1974), looking specifically at women's relationship to patriarchal language. (shrink)

Volume 20, Issue 8, August 2020, Page W12-W13.

RésuméJ'examine ici la plausibilité du perfectionnisme, compris comme une théorie morale dotée d'une structure conséquentialiste maximisante et du principe d'action suivant: maximise la valeur perfectionniste. Je soutiens que: 1) la structure en question ne répond pas aux préoccupations principales qui ont été responsables de l'intérêt récent pour ce type de théorie; 2) le principe d'action n'a que l'apparence de la précision; 3) nous ne pouvons promouvoir la valeur perfectionniste, vue comme une exigence morale, qu'en l'intégrant à un cadre moral pluraliste; (...) et 4) si nous l'intégrons à un cadre moral pluraliste, alors le principe requérant sa promotion ne peut pas être un principe de maximisation. (shrink)

Dieser Aufsatz betrifft Leibniz' Gedanken über Metaphysik in der Zeit von Dezember 1675 bis Dezember 1676, d. h. von den letzten Monaten seines Parisaufenthaltcs bis zum Beginn seines Aufenthaltes in Hannover. In dieser Zeit entwarf Leibniz Pläne für eine Abhandlung über Gott und die Welt und erwog die Möglichkeit, dieser Abhandlung eine deduktive Form zu geben. Der vorliegende Aufsatz entwickit und erläutert eine vermutete deduktive Version ¿ es metaphysischen Systems, die in den verstreuten Schriften dieser Periode entdeckt werden kann. Es (...) zeigt sieht, daß viel von Leibniz' reifer Philosophie bereits in diesem System enthalten ist. Jedoch findet sich kein Hinweis auf den dynamischen Charakter der Substanz und keine klare Formulierung der These, daß jeder Substanz ein vollständiger Begriff zukommt. Man findet vielleicht einige Andeutungen der späteren These, aber diese sind eher als Vorausdeutungen auf Leibniz' spätere Philosophie zu verstehen denn als konstitutive Teile des Systems von 1675/76. (shrink)

Research with nonhuman primates is essential to medical progress and will still be necessary for the foreseeable future. Almost all research scientists agree that animal research is critical to understanding basic biology, discovering new treatments for human (and animal) diseases, and maximizing the safety of new medicines while minimizing their harm to humans. All but two of the Nobel prizes in medicine awarded over the last one hundred years have depended on animal research, and the list of modern medicines, vaccines, (...) and other treatments, as well as basic science discoveries, is so extensive that it could not be adequately covered in even a huge volume. Increases in average life span in the last century are the result of improved public health measures, and many diseases may be related to lifestyle choices. But animal research has contributed to understanding these factors and to the development of vaccines and lifesaving treatments. The philosophical debate regarding the benefits and moral costs of animal research has also filled many volumes by ethicists and philosophers. The major arguments against the use of animals in medical research have been explicitly refuted by a few brave scientists, as well as implicitly by the vast majority of the working biomedical science community. My contribution to this discussion is to provide a personal perspective on my decision if, when, and how to use monkeys in research experiments on Parkinson disease. As a physician researcher, I have been working for many years to understand and cure Parkinson disease. (shrink)

Pushing past the constraints of postmodernism which cast "reason" and"religion" in opposition, God, the Gift, and Postmodernism, seizes the opportunity to question the authority of "the modern" and open the limits of possible experience, including the call to religious experience, as a new millennium approaches. Jacques Derrida, the father of deconstruction, engages with Jean-Luc Marion and other religious philosophers to entertain questions about intention, givenness, and possibility which reveal the extent to which deconstruction is structured like religion. New interpretations of (...) Kant, Heidegger, Husserl, and Derrida emerge from essays and discussions with distinguished philosophers and theologians from the United States and Europe. The result is that God, the Gift, and Postmodernism elaborates a radical phenomenology that stretches the limits of its possibility and explores areas where philosophy and religion have become increasingly and surprisingly convergent. Contributors include: John D. Caputo, John Dominic Crossan, Jacques Derrida, Robert Dodaro, Richard Kearney, Jean-Luc Marion, Frangoise Meltzer, Michael J. Scanlon, Mark C. Taylor, David Tracy, Merold Westphal and Edith Wyschogrod. (shrink)

This commentary critically examines two facets of Tracy Llanera's recent book Richard Rorty: Outgrowing Modern Nihilism. First, it considers her interpretation of Richard Rorty's redemptive project. It argues that, while Llanera succeeds in resolving tensions in Rorty's public‐private distinction, her account downplays the role of abnormal discourse within projects of self‐creation. Second, it raises several questions about Llanera's strategy for situating this redemptive project within debates concerning existential nihilism. On her view, one ought to follow Rorty in addressing the problem (...) of egotism instead of the problem of nihilism, since the former is prior to the latter. But it is not clear who counts as an egotist, or why egotists are especially prone to becoming nihilists. Moreover, there are reasons to think that egotism and nihilism are fundamentally different kinds of problems. (shrink)

Research on dyscalculia in neurodegenerative diseases is still scarce, despite high impact on patients’ independence and activities of daily living function. Most studies address Alzheimer’s Disease; however, patients with Parkinson’s Disease also have a higher risk for cognitive impairment while the relation to arithmetic deficits in financial contexts has rarely been studied. Therefore, the current exploratory study investigates deficits in two simple arithmetic tasks in financial contexts administered within the Clinical Dementia Rating in a sample of 100 PD patients. (...) Patients were classified as cognitively normal or mildly impaired according to Level I consensus criteria, and assessed using a comprehensive neuropsychological test battery, neurological motor examination, and sociodemographic and clinical questionnaires. In total, 18% showed arithmetic deficits: they were predominately female, had longer disease duration, more impaired global cognition, but minor signs of depression compared to PD patients without arithmetic deficits. When correcting for clinical and sociodemographic confounders, greater impairments in attention and visuo-spatial/constructional domains predicted occurrence of arithmetic deficits. The type of deficit did not seem to be arbitrary but seemed to involve impaired place × value processing frequently. Our results argue for the importance of further systematic investigations of arithmetic deficits in PD with sensitive tests to confirm the results of our exploratory study that a specific subgroup of PD patients present themselves with dyscalculia. (shrink)